| Primary Identifier | IPR033491 | Type | Family |
| Short Name | MID2 |
| description | MID2 shares high structural and functional similarities with MID1, an ubiquitin E3 ligase that regulates the turnover of microtubular protein phosphatase 2Ac. MID2 interacts with Astrin (a microtubule-organizing protein) and regulates Astrin levels to promote cell division []. MID1 and MID2 may play roles in regulating tissue remodelling in early development [].Mutations in the MID2 gene cause mental retardation, X-linked 101 (MRX101) []. |
