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Protein Coding Gene : Ppp2r2b protein phosphatase 2, regulatory subunit B, beta

Primary Identifier  MGI:1920180 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  72930
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable protein phosphatase regulator activity. Predicted to be involved in mitochondrion organization; positive regulation of neuron apoptotic process; and protein targeting to mitochondrion. Predicted to act upstream of or within apoptotic process. Predicted to be located in mitochondrial outer membrane. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytosol. Is expressed in several structures, including cranial ganglion; lung; sensory organ; tongue; and viscerocranium. Human ortholog(s) of this gene implicated in Alzheimer's disease; brain disease; breast cancer; and spinocerebellar ataxia type 12. Orthologous to human PPP2R2B (protein phosphatase 2 regulatory subunit Bbeta).
  • synonyms:
  • E130009M08Rik,
  • protein phosphatase 2, regulatory subunit B, beta,
  • RIKEN cDNA 6330404L05 gene,
  • 2900026H06Rik,
  • MGI:1917986,
  • PP2A-PR55B,
  • MGI:2442228,
  • Ppp2r2b,
  • RIKEN cDNA 2900026H06 gene,
  • PR55-BETA,
  • RIKEN cDNA E130009M08 gene,
  • SCA12,
  • 6330404L05Rik

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