| First Author | Secher T | Year | 2010 |
| Journal | Cancer Res | Volume | 70 |
| Issue | 5 | Pages | 1749-52 |
| PubMed ID | 20145153 | Mgi Jnum | J:158004 |
| Mgi Id | MGI:4437511 | Doi | 10.1158/0008-5472.CAN-09-3401 |
| Citation | Secher T, et al. (2010) Remote control of intestinal tumorigenesis by innate immunity. Cancer Res 70(5):1749-52 |
| abstractText | Chronic intestinal inflammation has been linked to the development of colorectal cancer. Recent studies suggest that during chronic inflammation, the innate immune system may facilitate colon tumorigenesis in genetically predisposed individuals in response to certain indigenous microorganisms and/or cell remnants. In these individuals, therapeutic approaches that reroute the innate immune system's inflammatory and antimicrobial activities might help prevent colon tumorigenesis and metastasis. |
