Primary Identifier | MGI:2148692 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Six5 |
Transmission | Germline | Strain of Origin | 129/Sv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Replacement of much of the first exon with an in-frame lacZ gene. A loxP flanked neomycin resistance cassette inserted 3' to the lacZ gene was removed via Cre-mediated recombination in ES cells prior to the production of chimeric mice. Beta-galactosidase is expressed from this allele under the control of the endogenous promoter elements. |