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Protein Coding Gene : Tub TUB bipartite transcription factor

Primary Identifier  MGI:2651573 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  22141
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable G protein-coupled receptor binding activity and intraciliary transport particle A binding activity. Acts upstream of or within several processes, including phagocytosis, recognition; photoreceptor cell maintenance; and protein localization to non-motile cilium. Located in cytosol and extracellular region. Is expressed in several structures, including central nervous system; endocrine gland; musculature; peripheral nervous system; and sensory organ. Used to study obesity. Orthologous to human TUB (TUB bipartite transcription factor).
PHENOTYPE: Homozygous mutants exhibit a late-developing obesity with hyperinsulinemia, retinal degeneration, and hearing loss associated with death of both outer and inner hair cells. [provided by MGI curators]
  • synonyms:
  • MGI:97886,
  • rd5,
  • tubby,
  • Tub,
  • MGD-MRK-15299,
  • MGD-MRK-13815,
  • tub,
  • retinal degeneration 5,
  • TUB bipartite transcription factor,
  • MGI:98868

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For