Primary Identifier | MGI:2667614 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Dclre1c |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 5 and 6 were replaced with a floxed neo cassette inserted by homologous recombination. While normal transcript was undetected by RT-PCR analysis of homozygous mutant kidney tissue, truncated transcript comprised of exons 1 through 4 was detected. The shortened transcript lacked sequence encoding 2 of the 4 zinc binding motifs. |