| Primary Identifier | MGI:3505556 | Allele Type | Transgenic |
| Attribute String | Reporter | Gene | Tg(CAG-Bgeo/ALPP)1Lbe |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| description | Cre excision of lacZ and the neomycin resistance gene results in expression of the ALPP reporter. |
| molecularNote | The transgene contains the CMV enhancer/chicken beta-actin promoter, a floxed Beta-geo reporter/SV40 polyadenylation signal segment, and the human placental alkaline phosphatase gene followed by a rabbit Hbb polyadenylation sequence. In transgenic mice expression of lacZ is widespread, with notable exceptions being erythrocytes, chondrocytes and adipocytes. This expression is observed throughout all embryonic and adult stages. |
