Primary Identifier | IPR039240 | Type | Family |
Short Name | FAM3D |
description | FAM3D inhibits glucagon secretion via MKP1-dependent suppression of ERK1/2 signaling. As dysregulated glucagon secretion is a characteristic of type 2 diabetes, FAM3D could have a therapeutic potential []. FAM3D is constitutively expressed in the gastrointestinal tract []and could play a role in gastrointestinal homeostasis and inflammation through its receptors FPR1 and FPR2 []. |