First Author | King B | Year | 2012 |
Journal | Cancer Cell | Volume | 21 |
Issue | 4 | Pages | 453-5 |
PubMed ID | 22516255 | Mgi Jnum | J:189333 |
Mgi Id | MGI:5445060 | Doi | 10.1016/j.ccr.2012.03.026 |
Citation | King B, et al. (2012) Hijacking T cell differentiation: new insights in TLX function in T-ALL. Cancer Cell 21(4):453-5 |
abstractText | TLX1 and TLX3 are two closely-related homeobox transcriptional repressors frequently misexpressed and translocated in T cell acute lymphoblastic leukemia (T-ALL). In this issue of Cancer Cell, Dadi et al. provide new insights into how these factors are recruited by ETS-1 to the TCRalpha enhancer and actively repress differentiation. |