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Publication : Hijacking T cell differentiation: new insights in TLX function in T-ALL.

First Author  King B Year  2012
Journal  Cancer Cell Volume  21
Issue  4 Pages  453-5
PubMed ID  22516255 Mgi Jnum  J:189333
Mgi Id  MGI:5445060 Doi  10.1016/j.ccr.2012.03.026
Citation  King B, et al. (2012) Hijacking T cell differentiation: new insights in TLX function in T-ALL. Cancer Cell 21(4):453-5
abstractText  TLX1 and TLX3 are two closely-related homeobox transcriptional repressors frequently misexpressed and translocated in T cell acute lymphoblastic leukemia (T-ALL). In this issue of Cancer Cell, Dadi et al. provide new insights into how these factors are recruited by ETS-1 to the TCRalpha enhancer and actively repress differentiation.
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