| Primary Identifier | MGI:1922667 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 239405 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Enables heparin binding activity. Acts upstream of or within several processes, including embryonic limb morphogenesis; negative regulation of odontogenesis of dentin-containing tooth; and respiratory system development. Located in cell surface and extracellular region. Is expressed in several structures, including brain; jaw; limb; pelvic urethra; and sensory organ. Human ortholog(s) of this gene implicated in tetraamelia syndrome 2. Orthologous to human RSPO2 (R-spondin 2). PHENOTYPE: Homozygous mice display perinatal lethality, cleft palate, lung hypoplasia, asymmetric limb malformations and abnormal renal development. Heterozygous females display reduced fertility with age. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
