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Protein Coding Gene : Clec4b1 C-type lectin domain family 4, member b1

Primary Identifier  MGI:1917060 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  69810
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable carbohydrate binding activity. Acts upstream of or within positive regulation of release of sequestered calcium ion into cytosol. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC4C (C-type lectin domain family 4 member C).
PHENOTYPE: Mice homozygous for a null allele exhibit reduced numbers of monocyte-derived inflammatory cells at mycobacterial infection sites, impaired IFN-gamma production by T cells and increased bacterial load. [provided by MGI curators]
  • synonyms:
  • C-type lectin domain family 4, member b1,
  • DCARbeta,
  • DCAR,
  • 1810046I24Rik,
  • RIKEN cDNA 1810046I24 gene,
  • Clec4b1,
  • mDcar2

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