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Publication : Isolation of cDNA clones encoding the mouse protein V-1.

First Author  Pennica D Year  1995
Journal  Gene Volume  158
Issue  2 Pages  305-6
PubMed ID  7607560 Mgi Jnum  J:26498
Mgi Id  MGI:73944 Citation  Pennica D, et al. (1995) Isolation of cDNA clones encoding the mouse protein V-1. Gene 158(2):305-6
abstractText  The amino acid (aa) sequence of rat V-1, a developmentally regulated brain protein, was used to isolate clones encoding mouse V-1, a protein of 118 aa, from an embryoid body cDNA library. The aa sequences of rat and mouse V-1 are identical. V-1 shares several properties (including a 23 of 24 aa match of a tryptic peptide) with myotrophin, a protein that induces cardiac myocyte hypertrophy. Attempts to show that V-1 produced in Escherichia coli could induce the cardiac myocyte hypertrophy ascribed to myotrophin were unsuccessful.
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