Primary Identifier | MGI:2159338 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Wasl |
Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This allele is a derivative of Wasltm1Wehl. Cre-mediated recombination in vivo removed exons 6-9 in the germline, eliminating the effector domains and leaving a single loxP site in place of the deleted sequence. The authors predict that splicing exon 5 to the remaining exon 10 would create a premature stop codon. |