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Allele : Tg(Syn1-ADCY7)11004Btab transgene insertion 11004, Boris Tabakoff

Primary Identifier  MGI:3695128 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Syn1-ADCY7)11004Btab
Strain of Origin  (C57BL/6 x SJL)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene consists of a 4.5 kb fragment of the rat synapsin I promotor, a 3.6 kb fragment of human ADCY7 cDNA, and a 650 bp fragment of the human growth hormone gene. Expression is confined to the central nervous system. Three lines (11004, 11012, and 10115) with high levels of expression were created which all have identical phenotype. One of these lines (10115) was generated using FVB/N oocytes while the other 2 used hybrid C57BL/6 x SJL oocytes. This is a representative record for all three lines
  • mutations:
  • Insertion
  • synonyms:
  • Adcy7<huTG>,
  • Adcy7<huTG>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele