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Protein Coding Gene : Pla2g1b phospholipase A2, group IB, pancreas

Primary Identifier  MGI:101842 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  18778
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables phospholipase A2 activity and signaling receptor binding activity. Predicted to be involved in several processes, including defense response to other organism; glycerophospholipid metabolic process; and positive regulation of podocyte apoptotic process. Predicted to act upstream of or within phospholipid catabolic process. Located in extracellular region. Is expressed in liver; lung; and spleen. Orthologous to human PLA2G1B (phospholipase A2 group IB).
PHENOTYPE: Mice homozygous for disruptions in this gene display abnormalities in lipid absorption, increased insulin sensitivity and improved glucose tolerance. [provided by MGI curators]
  • synonyms:
  • phospholipase A2, group IB, pancreas,
  • Pla2a,
  • MGD-MRK-18663,
  • phospholipase A2 polypeptide A (pancreatic),
  • sPLA2IB,
  • MGD-MRK-13343,
  • Pla2g1b

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

10 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For