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Protein Coding Gene : Plekha2 pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
Primary Identifier  MGI:1928144 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  83436
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables PDZ domain binding activity and phosphatidylinositol-3,4-bisphosphate binding activity. Predicted to be involved in positive regulation of cell-matrix adhesion. Predicted to be located in nucleus and plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and membrane. Is expressed in several structures, including bone; central nervous system; jaw; thymus primordium; and vomeronasal organ. Orthologous to human PLEKHA2 (pleckstrin homology domain containing A2).
PHENOTYPE: Mice homozygous for a knock-in allele are viable. [provided by MGI curators]
  • synonyms:
  • pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2,
  • expressed sequence W91773,
  • W91773,
  • MGI:2142717,
  • MGI:2142635,
  • RIKEN cDNA 6430512N22 gene,
  • MGI:1923451,
  • expressed sequence AU041791,
  • AI851530,
  • Plekha2,
  • MGI:2142903,
  • expressed sequence AI851530,
  • 6430512N22Rik,
  • TAPP2,
  • AU041791
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