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Protein Coding Gene : Cops6 COP9 signalosome subunit 6

Primary Identifier  MGI:1349439 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  26893
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable metallopeptidase activity. Predicted to be involved in protein deneddylation. Part of COP9 signalosome. Is expressed in several structures, including brown fat; central nervous system; male reproductive system; sensory organ; and urinary system. Orthologous to human COPS6 (COP9 signalosome subunit 6).
PHENOTYPE: Mice homozygous for a gene trap allele or a transgenic gene disruption exhibit embryonic lethality. Mice heterozygous for a gene trap allele exhibit increased sensitivity to irradiation and decreased incidence of ionizing radiation-induced tumors. [provided by MGI curators]
  • synonyms:
  • VIP/MOV34,
  • COP9 complex S6,
  • COP9 signalosome subunit 6,
  • Cops6,
  • Sgn3

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

13 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For