| Primary Identifier | MGI:1913945 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 66695 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable calcium ion binding activity. Involved in negative regulation of tooth mineralization and negative regulation of transforming growth factor beta receptor signaling pathway. Located in extracellular matrix. Is expressed in several structures, including alimentary system; forelimb; genitourinary system; integumental system; and skeleton. Human ortholog(s) of this gene implicated in ankylosing spondylitis; degenerative disc disease; and osteoarthritis. Orthologous to human ASPN (asporin). PHENOTYPE: Mice homozygous for a null allele exhibit increased skin mechanical toughness with altered glycosaminoglycan content and structure in the skin. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
