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Allele : Il12b<tm1.1Lky> interleukin 12b; targeted mutation 1.1, Richard M Locksley
Primary Identifier  MGI:3663346 Allele Type  Targeted
Attribute String  Reporter Gene  Il12b
Transmission  Germline Strain of Origin  129S4/SvJae-Tg(Prm-cre)70Og
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert an internal ribosomal entry site (IRES)-enhanced yellow fluorescent protein (EYFP; Clontech) sequence (followed by a bovine growth hormone poly(A) signal and a loxP site flanked neomycin resistance gene cassette) downstream of the stop codon in exon 8 of the endogenous gene. The construct was electroporated into ES cells that contain the Tg(Prm-cre)70Og transgene that effects the removal of the neo cassette through cre-mediated recombination in the male germline.
  • mutations:
  • Insertion
  • synonyms:
  • yet40,
  • p40 (y),
  • IL-12/p40 y,
  • yet40,
  • p40-IRES-eYFP,
  • p40 (y),
  • Il12b<tm1(EYFP)Lky>,
  • IL-12/p40 y,
  • Il12b<tm1(EYFP)Lky>,
  • p40-IRES-eYFP
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

53 Publication categories

Trail: Allele




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