| Type | MGI:General | Description | after induction with 2.5% dextran sodium sulfate (DSS) and compared to DSS-treated wild-type mice higher mortality lower body weight reduced colon length, also in DSS-treated wild-type and mutant recipients of mutant bone marrow significantly elevated accumulation of macrophages, neutrophils, B cells, CD4+ T cells and CD8+ T cells, also in DSS-treated wild-type and mutant recipients of mutant bone marrow markedly higher levels of pro-inflammatory cytokines and chemokines such as Tnf, Il1b, Il6, Cxcl1 and Ccl2/Mcp1 increased histological damage score, also in DSS-treated wild-type and mutant recipients of mutant bone marrow |
