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Protein Domain : CENP-C, middle DNMT3B-binding domain

Primary Identifier  IPR028931 Type  Domain
Short Name  CENP-C_mid
description  CENP-C is a component of the centromere assembly complex in eukaryotes. CENP-C recruits the DNA methyltransferases DNMT3B, in order to establish the necessary epigenetic DNA-methylation essential for maintenance of chromatin structure and genomic stability. This entry represents the middle DNMT3B binding region of CENP-C. Binding of CENP-C and DNMT3B to DNA occurs at both centromeric and peri-centromeric satellite repeats. CENP-C and DNMT3B regulate the histone code in these regions [, , ].
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3 Protein Domain Regions

Trail: ProteinDomain




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