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Protein Coding Gene : Myh4 myosin, heavy polypeptide 4, skeletal muscle

Primary Identifier  MGI:1339713 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  17884
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable actin filament binding activity; double-stranded RNA binding activity; and microfilament motor activity. Acts upstream of or within response to activity. Predicted to be located in myofibril. Predicted to be part of myosin II complex. Predicted to be active in cytoplasm and myosin filament. Is expressed in several structures, including brown fat; heart; limb segment; musculature; and paraxial mesenchyme. Orthologous to human MYH4 (myosin heavy chain 4).
PHENOTYPE: Homozygotes for a targeted null mutation exhibit decreased growth and muscle defects including reduced muscle mass, muscle fiber loss, compensatory fiber hypertrophy, and impaired strength. [provided by MGI curators]
  • synonyms:
  • myosin heavy chain, skeletal muscle, adult fast,
  • Minimsc,
  • MGI:2144213,
  • Myh4,
  • Myhsf,
  • MyHC-IIb,
  • mini muscle,
  • Minmus,
  • myosin, heavy polypeptide 4, skeletal muscle,
  • expressed sequence AI506973,
  • MGI:4420408,
  • AI506973,
  • MM,
  • MHC2B,
  • MGI:1261431,
  • MYH-2B

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For