| Primary Identifier | MGI:1921622 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 209012 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Acts upstream of or within several processes, including cerebrospinal fluid circulation; cilium organization; and nervous system development. Is expressed in brain. Used to study hydrocephalus and schizophrenia. Orthologous to human ULK4 (unc-51 like kinase 4). PHENOTYPE: Homozygotes for a null allele show reduced body size, hydrocephaly, dilated brain ventricles, otitis media, and premature death. Hypomorphic mice show partial corpus callosum aplasia, hydrocephaly, subcommissural organ and ependymal motile ciliary defects, aqueduct stenosis, and impaired CSF flow. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
