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Protein Coding Gene : Mrs2 MRS2 magnesium transporter

Primary Identifier  MGI:2685748 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  380836
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable magnesium ion transmembrane transporter activity. Predicted to be involved in lactate metabolic process and mitochondrial magnesium ion transmembrane transport. Predicted to act upstream of or within monoatomic ion transport. Located in mitochondrion. Orthologous to human MRS2 (magnesium transporter MRS2).
PHENOTYPE: Homozygous knockout affects mitochondrial Mg2+ uptake and leads to protection against LPS-induced septic shock. [provided by MGI curators]
  • synonyms:
  • Mrs2,
  • LOC380836,
  • MRS2-like, magnesium homeostasis factor (S. cerevisiae),
  • gene model 902, (NCBI),
  • MRS2 magnesium transporter,
  • Mrs2l,
  • Gm902

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For