| Primary Identifier | MGI:5818053 | Allele Type | Targeted |
| Attribute String | Null/knockout, Recombinase | Gene | Nkx2-2 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | The entire ORF of the Nkx2-2 gene including most of exon1, intron 1, and exon 2 is replaced by the codonimproved Cre-ORF and the polyA addition signal sequence (pA) followed by FRT-flanked neomycin selection cassette (PGK-neo) by homologous recomibination in ES cells. Chimeras were produced by ES cell injection into C57BL/6J blastocysts. The resulting line was bred with Flp deleter mice to remove the neo cassette. |
