| Primary Identifier | MGI:2448704 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 71562 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable arylformamidase activity. Acts upstream of or within tryptophan catabolic process to kynurenine. Located in cytoplasm. Is expressed in genitourinary system; gut; nervous system; and respiratory system. Orthologous to human AFMID (arylformamidase). PHENOTYPE: Mice homozygous for a knock-out allele exhibit polydipsia, polyuria and hyperglycemia. Mice homozygous for a full exon 2 deletion show impaired glucose tolerance due to reduced insulin secretion associated with reduced islet mass. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
