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Protein Coding Gene : Lrrc8d leucine rich repeat containing 8D
Primary Identifier  MGI:1922368 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  231549
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables volume-sensitive anion channel activity. Involved in intracellular glucose homeostasis. Located in plasma membrane. Is expressed in several structures, including nasal cavity epithelium; nervous system; submandibular gland primordium; tooth; and vibrissa. Orthologous to human LRRC8D (leucine rich repeat containing 8 VRAC subunit D).
PHENOTYPE: Mice homozygous for a null allele exhibit normal response to viral infection. [provided by MGI curators]
  • synonyms:
  • leucine rich repeat containing 5,
  • MGI:1920077,
  • 4930525N13Rik,
  • RIKEN cDNA 4930525N13 gene,
  • 2810473G09Rik,
  • Lrrc5,
  • leucine rich repeat containing 8D,
  • RIKEN cDNA 2810473G09 gene,
  • Lrrc8d
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Features --> Cross References

Genome

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0 Canonical

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0 Exons

0 Genomic Clusters

3 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

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Interactions

2 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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