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Protein Coding Gene : Elavl1 ELAV like RNA binding protein 1

Primary Identifier  MGI:1100851 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  15568
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables lncRNA binding activity and mRNA 3'-UTR AU-rich region binding activity. Involved in post-transcriptional regulation of gene expression; protein import into nucleus; and regulation of stem cell population maintenance. Acts upstream of or within positive regulation of translation. Located in several cellular components, including cytoplasmic stress granule; endoplasmic reticulum; and sarcoplasm. Part of ribonucleoprotein complex. Is active in cytoplasmic vesicle; glutamatergic synapse; and postsynapse. Is expressed in several structures, including alimentary system; central nervous system; connective tissue; early conceptus; and genitourinary system. Orthologous to human ELAVL1 (ELAV like RNA binding protein 1).
PHENOTYPE: Homozygous inactivation of this gene leads to embryonic growth retardation and midgestational lethality due to placental failure resulting from extraembryonic trophoblast defects. [provided by MGI curators]
  • synonyms:
  • MGI:2142902,
  • Elavl1,
  • HuR,
  • W91709,
  • HU-antigen A,
  • ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R),
  • RIKEN cDNA 2410055N02 gene,
  • 2410055N02Rik,
  • MGI:1920936,
  • Hua,
  • ELAV like RNA binding protein 1,
  • expressed sequence W91709

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Genome

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0 Exons

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

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Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

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Disease

Mouse features --> Human diseases

Literature

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