| First Author | Ishida J | Year | 2000 |
| Journal | Cancer Lett | Volume | 159 |
| Issue | 2 | Pages | 135-40 |
| PubMed ID | 10996724 | Mgi Jnum | J:64661 |
| Mgi Id | MGI:1889754 | Doi | 10.1016/s0304-3835(00)00538-3 |
| Citation | Ishida J, et al. (2000) Antitumor-promoting effects of cyclic diarylheptanoids on epstein-barr virus activation and two-stage mouse skin carcinogenesis. Cancer Lett 159(2):135-40 |
| abstractText | Eleven cyclic diarylheptanoids were screened as potential antitumor promoters by examining the ability of the compounds to inhibit Epstein-Barr virus early antigen activation (induced by 12-O-tetradecanoylphorbol-13-acetate) in Raji cells. 13-Oxomyricanol and myricanone showed the highest activity and also exhibited remarkable inhibitory effects on mouse skin tumor promotion in an in vivo two-stage carcinogenesis test. These data suggest that certain diarylheptanoids might be valuable antitumor promoters and/or chemopreventors. |
