Primary Identifier | MGI:1916375 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 69125 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable poly(A)-specific ribonuclease activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay and positive regulation of cell population proliferation. Predicted to act upstream of or within regulation of translation and regulatory ncRNA-mediated gene silencing. Predicted to be located in nucleus. Predicted to be part of CCR4-NOT core complex. Predicted to be active in P-body. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and hemolymphoid system gland. Orthologous to human CNOT8 (CCR4-NOT transcription complex subunit 8). PHENOTYPE: Mice homozygous for a null allele exhibit lethality prior to E10.5. [provided by MGI curators] |