| Primary Identifier | MGI:6758671 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Kdm6b |
| Transmission | Germline | Strain of Origin | C57BL/6N-A<tm1Brd> |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | KOMP-CSD |
| molecularNote | The insertion of the L1L2_Bact_P cassette created a deletion of size 5536 starting at position 69291471 and ending at position 69297007 of Chromosome 11 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. The lacZ cassette was removed through subsequent flp-mediated recombination in allele Kdm6btm1(KOMP)Wtsi. |
