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Protein Coding Gene : Grk5 G protein-coupled receptor kinase 5

Primary Identifier  MGI:109161 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  14773
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable beta-adrenergic receptor kinase activity and protein serine/threonine kinase activity. Involved in fat cell differentiation. Predicted to be located in cytosol; nucleus; and plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and immune system. Orthologous to human GRK5 (G protein-coupled receptor kinase 5).
PHENOTYPE: Homozygous mutation of this gene results in a decrease in thermal pain sensation. Mice homozygous for a knock-out allele exhibit decreased response of heart to induced stress. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-38205,
  • Gprk5,
  • Grk5,
  • G protein-coupled receptor kinase 5,
  • G protein-receptor coupled kinase 5

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For