First Author | Clouston WM | Year | 1989 |
Journal | FEBS Lett | Volume | 255 |
Issue | 2 | Pages | 419-22 |
PubMed ID | 2792385 | Mgi Jnum | J:10025 |
Mgi Id | MGI:58482 | Doi | 10.1016/0014-5793(89)81136-6 |
Citation | Clouston WM, et al. (1989) The angiotensinogen gene is located on mouse chromosome 8. FEBS Lett 255(2):419-22 |
abstractText | We have recently identified a cis-acting genetic lesion affecting angiotensinogen gene expression in testis and salivary gland. Accordingly, the angiotensinogen gene was assigned to mouse chromosome 8 by screening a series of hybrid cell lines for retention of mouse angiotensinogen sequences by genomic Southern analysis. In AKXD recombinant inbred mice, the angiotensinogen gene is 2.4 +/- 1.8 centiMorgan from Rn7S-8,a 7S RNA gene located on chromosome 8 (Taylor, B.A., personal communication). However, the segregation of salivary and testicular angiotensinogen expression phenotypes into inbred mouse strains was not concordant with the known chromosome 8 proviruses Emv-2, Mtv-21, Xmv-12 or Xmv-26. |