Primary Identifier | MGI:1915033 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 226747 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable DNA binding activity. Predicted to be involved in nuclear pore complex assembly and regulation of cytokinesis. Predicted to act upstream of or within cell division; mRNA transport; and protein transport. Located in cytoplasm and nuclear matrix. Is expressed in several structures, including cardiovascular system; central nervous system; early conceptus; genitourinary system; and hemolymphoid system. Orthologous to human AHCTF1 (AT-hook containing transcription factor 1). PHENOTYPE: Homozygous null mice die between E3.5 and E5.5. The inner cell mass cells exhibit impaired proliferation and apoptosis when grown in culture. [provided by MGI curators] |