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Allele : Adrb1<tm1.1Rjl> adrenergic receptor, beta 1; targeted mutation 1.1, Robert J Lefkowitz

Primary Identifier  MGI:4839639 Allele Type  Targeted
Gene  Adrb1 Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  The final serine residue (the third from the end) was mutated to alanine to prohibit PDZ protein (post synaptic density protein (PSD95, Dlg4), Drosophila disc large tumor suppressor (DlgA; Dlg1), and zonula occludens-1 protein (zo-1; Tjp1)) binding. A residual loxP site is located in the 3' UTR after excision of a loxP-flanked neomycin cassette.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele