Primary Identifier | IPR029308 | Type | Domain |
Short Name | FANCI_S1 |
description | FANCI and FANCD2 form a complex central to the Fanconi anemia (FA) pathway, which is essential for the repair of DNA interstrand cross-links. FANCI has four distinct alpha solenoid (α-α superhelical) segments (S1-S4). Two mostly helical segments intervene between solenoids 1 and 2 (HD1), and between solenoids 2 and 3 (HD2) [].This is the solenoid 1 (S1) domain of the Fanconi anemia group I protein (FANCI). |