| First Author | Kameyama T | Year | 1996 |
| Journal | Biochem Biophys Res Commun | Volume | 226 |
| Issue | 2 | Pages | 396-402 |
| PubMed ID | 8806646 | Mgi Jnum | J:35259 |
| Mgi Id | MGI:82711 | Doi | 10.1006/bbrc.1996.1367 |
| Citation | Kameyama T, et al. (1996) Identification of plexin family molecules in mice. Biochem Biophys Res Commun 226(2):396-402 |
| abstractText | By screening of E17.5 mouse brain cDNA libraries, we isolated two cDNAs encoding new plexin-like proteins. Sequencing revealed that these two proteins were type 1 membrane proteins which showed over 60% identity at the amino acid level to mouse plexin 1. Moreover, putative extracellular segments of these two proteins had three repeats of a cysteine-rich domain which is a common motif for plexin proteins. Thus, we named these two proteins mouse plexin 2 and mouse plexin 3. We obtained mouse plexin 3 cDNA clones in which a part of protein-coding region was deleted. Also, Northern blot analysis showed molecular heterogeneity in mouse plexin 2 mRNAs. These findings indicate that in the mouse, plexins comprise a molecular family (the plexin family). |
