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Protein Coding Gene : Abcb5 ATP-binding cassette, sub-family B member 5
Primary Identifier  MGI:1924956 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  77706
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable ATPase-coupled transmembrane transporter activity and efflux transmembrane transporter activity. Involved in eye development. Located in plasma membrane. Is expressed in corneo-scleral junction. Orthologous to human ABCB5 (ATP binding cassette subfamily B member 5).
PHENOTYPE: Mice homozygous for a null allele display limbal stem cell abnormalities, impaired cornea development and repair, and retinal abnormalities. [provided by MGI curators]
  • synonyms:
  • ATP-binding cassette, sub-family B member 5,
  • Abcb5,
  • 9230106F14Rik,
  • RIKEN cDNA 9230106F14 gene
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Features --> Cross References

Genome

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1 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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