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Allele : Kdm5b<em1Zhanz> lysine demethylase 5B; endonuclease-mediated mutation 1, Zhenzhen Zhan

Primary Identifier  MGI:7524555 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Kdm5b
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a 428 bp deletion containing the JmjC domain, which is responsible for its demethylase activity, resulting in a frameshift and loss of function.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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2 Publication categories

Trail: Allele