Primary Identifier | MGI:7524555 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Kdm5b |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology generated a 428 bp deletion containing the JmjC domain, which is responsible for its demethylase activity, resulting in a frameshift and loss of function. |