| Primary Identifier | MGI:1342273 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 14873 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable glutathione dehydrogenase (ascorbate) activity and glutathione transferase activity. Predicted to be involved in several processes, including L-ascorbic acid biosynthetic process; cellular response to arsenic-containing substance; and regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum. Predicted to be located in several cellular components, including basement membrane; cell body; and nuclear membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and Parkinson's disease. Orthologous to human GSTO1 (glutathione S-transferase omega 1). PHENOTYPE: Mice homozygous for a mutant allele do not display abnormal arsenate metabolism following acute arsenate exposure. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
