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Comment :

Type  MGI:General Description  incomplete separation of the hindgut from the urogenital sinus (UGS) is observed in some embryos at E17 males have a fistulous connection between hindgut and dorsal surface of UGS; females show similar defects at E17 at E14 ventral mesenchymal cell density of UGS is reduced relative to E14 wild-type embryos indicating defective development of the ventral mesenchyme pad; this reduced cell density occurs along with decreased epithelial cell proliferation in the ventral UGS at P1 this is observed as reduction in ventral mesenchyme pad thickness and density