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Publication : Cloning, expression and tissue distribution of the gene encoding rat fibroblast growth factor receptor subtype 4.

First Author  Horlick RA Year  1992
Journal  Gene Volume  120
Issue  2 Pages  291-5
PubMed ID  1398143 Mgi Jnum  J:60851
Mgi Id  MGI:1354004 Doi  10.1016/0378-1119(92)90108-2
Citation  Horlick RA, et al. (1992) Cloning, expression and tissue distribution of the gene encoding rat fibroblast growth factor receptor subtype 4. Gene 120(2):291-5
abstractText  The rat homologue of the gene encoding the fibroblast growth factor receptor subtype 4 (FGFR4) was cloned from rat lung mRNA, and the cDNA sequence was found to be 95% similar and 92% identical to the human homologue. Northern blot analysis of adult rat tissues demonstrated that a 3.1-kb mRNA encoding FGFR4 is detectable only in the lung and kidney. The receptor variant described here encodes two potential immunoglobulin-like domains, 21 hydrophobic amino acids encoding a potential transmembrane domain, and a split tyrosine kinase motif. However, the acidic box and hydrophobic signal peptide domains are not present in this cDNA isolate.
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