| Primary Identifier | MGI:1351455 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 22121 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables mRNA binding activity. A structural constituent of ribosome. Involved in cellular response to type II interferon and negative regulation of translation. Acts upstream of or within several processes, including lung morphogenesis; macrophage chemotaxis; and response to lipopolysaccharide. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Orthologous to human RPL13A (ribosomal protein L13a). PHENOTYPE: Homozygotes lacking snoRNAs encoded by introns of this gene show altered mitochondrial metabolism, lower reactive oxygen species tone, enhanced glucose-stimulated insulin secretion and glucose tolerance, reduced oxidative stress responses in pancreatic islets, and resistance to diabetogenic stimuli. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
