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Protein Coding Gene : Pafah2 platelet-activating factor acetylhydrolase 2

Primary Identifier  MGI:2140321 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  100163
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable 1-alkyl-2-acetylglycerophosphocholine esterase activity and platelet-activating factor acetyltransferase activity. Predicted to be involved in negative regulation of apoptotic process. Predicted to act upstream of or within lipid catabolic process. Predicted to be located in endoplasmic reticulum and membrane. Is expressed in alimentary system; nervous system; and respiratory system. Orthologous to human PAFAH2 (platelet activating factor acetylhydrolase 2).
PHENOTYPE: Mice homozygous for a null allele exhibit increased sensitivity to hepatic injury. [provided by MGI curators]
  • synonyms:
  • MGI:1919176,
  • platelet-activating factor acetylhydrolase 2,
  • AI507170,
  • expressed sequence AI507170,
  • Pafah2,
  • 2310074E22Rik,
  • RIKEN cDNA 2310074E22 gene

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Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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0 Driver For