| Primary Identifier | MGI:5911053 | Allele Type | Targeted |
| Gene | Npr2 | Transmission | Germline |
| Strain of Origin | (129 x C57BL/6J)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A floxed construct containing a Npr2 cDNA encoding exons 8- 22, and IRES site, eGFP gene, and FRT flanked pgk-neo casstte was inserted in intron 7 and point mutations in the seven serine and threonine sites in exons 8 and 9 were introduced via homologous recombination. The point mutations converted the serine and threonine codons to glutamate codons. Cre-mediated recombination removed the entire construct. The resulting protein behaves as if it is constitutively phosphorylated. |
