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Protein Coding Gene : Fpr2 formyl peptide receptor 2

Primary Identifier  MGI:1278319 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  14289
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables N-formyl peptide receptor activity and amyloid-beta binding activity. Involved in cellular response to amyloid-beta; positive chemotaxis; and positive regulation of superoxide anion generation. Acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Orthologous to human FPR2 (formyl peptide receptor 2).
PHENOTYPE: Mice homozygous for a targeted reporter allele exhibit altered leukocyte responses and experimentally induced inflammation. [provided by MGI curators]
  • synonyms:
  • Fpr-rs2,
  • formyl peptide receptor, related sequence 2,
  • E330010I07Rik,
  • RIKEN cDNA E330010I07 gene,
  • Fpr2,
  • formyl peptide receptor 2,
  • MGI:2442028

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

12 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For