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Comment :

Type  MGI:General Description  CD4 T cells are resistant to anergy induced in vitro as measured by cellular proliferation in response to anti-CD3 restimulation proliferation rates are 5-10 fold higher upon restimulation compared to wild-type controls CD4 T cells expressing the Vbeta8 chain continue to proliferate upon restimulation with the superantigen SEB compared to CD4 T cells from control mice that are tolerized and do not proliferate in response to restimulation