| Primary Identifier | MGI:105307 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 545622 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable several functions, including ATPase binding activity; phosphotyrosine residue binding activity; and sodium channel regulator activity. Predicted to be involved in negative regulation of membrane protein ectodomain proteolysis; negative regulation of mitotic cell cycle; and regulation of membrane depolarization during action potential. Predicted to be located in cytoskeleton and plasma membrane. Predicted to be active in cytoplasm and cytoplasmic side of plasma membrane. Is expressed in several structures, including cranial ganglion; gut; nasal epithelium; submandibular gland primordium; and urinary system. Orthologous to human PTPN3 (protein tyrosine phosphatase non-receptor type 3). PHENOTYPE: Mice homozygous for a null allele exhibit increased body weight, especially in males, and male mice exhibit increased bone mineral content. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
