Primary Identifier | IPR042999 | Type | Family |
Short Name | CTNNBIP1 |
description | Beta-catenin-interacting protein 1 (CTNNBIP1), also known as ICAT, is a suppressor of the Wnt/beta-catenin signaling pathway. It negatively regulates beta-catenin co-transcriptional activity by competing with TCF/LEF factors in their binding to beta-catenin superhelical core [, , ]. |