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Protein Coding Gene : St6galnac2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
Primary Identifier  MGI:107553 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  20446
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to be located in Golgi apparatus and membrane. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; lung; and mammary gland. Orthologous to human ST6GALNAC2 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2).
PHENOTYPE: Mice homozygous for a knockout allele exhibit decreased body weight, decreased IgQ, increased B cell proliferation, increased pre-B cell number, abnormal erythropoiesis, increased ALT, decreased creatinine level and prominent spleen germinal center. [provided by MGI curators]
  • synonyms:
  • Siat7b,
  • ST6GalNAc II,
  • St6galnac2,
  • ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2,
  • MGD-MRK-36124,
  • Siat7,
  • sialyltransferase 7 ((alpha-N-acetylneuraminyl 2,3-beta-galactosyl-1,3)-N-acetyl galactosaminde alpha-2,6-sialyltransferase) B,
  • sialyltransferase 7 ((alpha-N-acetylneuraminyl 2,3-beta-galactosyl-1,3)-N-acetyl galactosaminde alpha-2,6-sialyltransferase B,
  • sialyltransferase 7
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